Thursday, July 19, 2012

Blogging the Human Genome

Say the fusion left Guy with a normal chromosome 12, a normal 13, and a 12-13 hybrid in each cell. During sperm production his body has to divide those three chromosomes into two cells, and there are only a few possible ways to divvy them. There?s {12} & {13, 12-13}, or {13} & {12, 12-13}, or {12, 13} & {12-13}. The first four sperms are either missing a chromosome or have a duplicate, practically a cyanide capsule for an embryo. The last two cases have the proper amount of DNA for a normal child. But only in the sixth case does Guy pass the fusion on. Overall, then, two-thirds of Guy?s children die in the womb, and just one-sixth inherit the fusion. And any Junior with the fusion would then face the same terrible odds trying to reproduce. Not a good recipe for spreading the fusion?and again, that?s still only 47 chromosomes, not 46.

Source: http://feeds.slate.com/click.phdo?i=c8e56171dd2ce519071203ff262d4108

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